Syllabus:
GS-3: Science and Technology- developments and their applications and effects in everyday life
Context:
Recently, scientists have shown that a special nanomaterial called graphitic carbon nitride (g-C₃N₄) can stimulate brain cells without the need for electrodes, lasers, or magnets.
More on the News
- This pioneering research published in the peer-reviewed journal ACS Applied Materials & Interfaces.
- The findings, published in ACS Applied Materials & Interfaces, show that graphitic carbon nitride promotes neuron growth, maturation, and communication by harnessing the brain’s own electrical activity.
Key Findings
- The findings offer a promising non-invasive alternative for treating brain disorders like Parkinson’s and Alzheimer’s diseases, which are on the rise globally with ageing populations.
- The material boosted dopamine production in lab-grown brain-like cells and reduced toxic proteins linked to Parkinson’s disease in animal models.
- Graphitic carbon nitride can naturally “talk” to neurons.
o When placed near nerve cells, it generates minute electric fields in response to the brain’s voltage signals.
o These fields open calcium channels on neurons, stimulating growth and strengthening connections between cells, without the need for any external device.
Potential Applications
- Neurological Therapy: This could be used to restore lost functions in patients with neurodegenerative diseases.
- Brain–Computer Interfaces (BCIs): It offers a safer, minimally invasive pathway for developing next-generation BCIs.
- Drug-Free Stimulation: It reduces reliance on pharmaceuticals for certain brain-related conditions.
Advantages Over Conventional Methods
- Non-invasive: It eliminates surgical risks associated with deep brain stimulation.
- Cost-effective: It is potentially cheaper than electrode- or magnet-based devices.
- Scalable: It can be adapted for large-scale clinical use in future.
Graphitic Carbon Nitride (g-C₃N₄)
- Identification: It is identified by scientists at the Institute of Nano Science and Technology (INST), an autonomous institute under the Department of Science and Technology (DST).
- Structure: A stacked two-dimensional material with tris-triazine-based patterns, containing carbon and nitrogen atoms.
- Electronic Properties: Electron-rich, with nitrogen atoms contributing to the valance band and carbon/nitrogen atoms contributing to the conduction band, allowing for visible light absorption.
- Stability: High physical, chemical, and thermal stability, along with high abrasion resistance and hardness.
Sources:
PIB
Sciencedirect